Postdoctoral Researcher
Core
Lead experimental efforts focused on 3D genome organization in cancer, integrating chromatin architecture with transcriptional and regulatory landscapes using bulk, single-cell, and spatial epigenomics approaches.
Role type
Postdoctoral Researcher (Experimental Epigenomics)
Builds
Independent research projects on 3D genome organization, high-impact publications, and translational research for precision oncology.
Domain
Oncology / Genomics / Epigenomics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
3D genome assays (Hi-C, HiChIP, Capture-C), chromatin conformation assays (HiChIP, HiC), NGS library preparation, ATAC-seq, CUT&RUN, CUT&Tag, organoid culture, single-cell multi-omics, spatial multi-omics, independent experimental design, manuscript preparation, grant development, trainee mentorship
Preferred skills
Computational analysis of genomic data (R/Python), experience with organoid culture systems, exposure to single-cell or spatial genomics technologies
Technologies
Hi-C, HiChIP, Capture-C, ATAC-seq, CUT&RUN, CUT&Tag, NGS, R, Python
Responsibilities
Design and execute independent research projects centered on 3D genome organization in cancer; Perform and optimize chromatin conformation assays; Generate and integrate complementary epigenomic datasets; Contribute to or initiate single-cell and spatial multi-omics projects; Work with patient-derived organoid models; Perform and optimize NGS library preparation protocols; Collaborate closely with computational scientists for data analysis and interpretation; Lead manuscript preparation and contribute to grant development; Mentor trainees and contribute to a collaborative lab environment
Seniority
Postdoctoral Fellow (Independent Researcher)
