Analytical Chemist- Oligonucleotide Testing
Core
Developing, optimizing, validating, and executing analytical methods for oligonucleotide API, drug substance, and drug product testing using HPLC/UHPLC and mass spectrometry.
Role type
Senior analytical chemist (oligonucleotide testing)
Builds
Identity, purity/impurity profiling, quantitation, and stability-indicating assessments for pharmaceutical clients
Domain
Pharmaceutical / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
HPLC/UHPLC method development and validation, Mass spectrometry (LC-MS/LC-MS/MS), GxP compliance, Troubleshooting instrumentation, Regulatory knowledge (ICH guidelines), Mentoring junior staff
Preferred skills
GC, UV/Vis, Dissolution testing, Project management with clients
Technologies
HPLC, UHPLC, IEX, SEC, LC-MS, LC-MS/MS, GC, UV/Vis
Responsibilities
Author methods, protocols and reports; Ensure data integrity and compliance within GxP environments; Provide technical leadership for routine testing and investigations; Train and mentor junior staff; Manage and discuss projects with clients
Seniority
Senior, hands-on IC