Synthetic DNA Process Development Scientist
Core
Develop, optimize, and scale chemical synthesis and purification processes for high-throughput oligonucleotide production.
Role type
Process development scientist (organic chemistry/oligonucleotides)
Builds
High-quality oligonucleotides for manufacturing
Domain
Life sciences / Oligonucleotide synthesis
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
organic synthesis, oligonucleotide synthesis, process scale-up, HPLC, ion-exchange purification, analytical chemistry (LC-MS), SOP authoring, lab mentorship
Preferred skills
GMP experience, automated synthesizer operation, modified nucleotides, high-throughput production
Technologies
HPLC, LC-MS, ion-exchange, automated DNA/RNA synthesizers
Responsibilities
Design and optimize chemical synthesis processes for nucleotides and oligonucleotides; Develop and improve oligonucleotide purification processes; Troubleshoot synthesis and purification challenges to improve yield and purity; Collaborate with manufacturing, QC, and engineering for process transfer; Author SOPs, batch records, and technical reports; Mentor lab technicians
Seniority
Mid-level, hands-on IC