Research Leader (In-vitro Pharmacology, Exploratory Sciences), London
Core
Lead a team of biologists to define and execute in vitro pharmacology strategies for novel therapeutic modalities (TPD, molecular glues, peptides) and generate ML-ready data to close the loop between computational predictions and wet-lab experiments.
Role type
Senior IC research leader (in vitro pharmacology) with team management responsibilities
Builds
Novel drug modalities and ML-ready experimental datasets
Domain
Biotech / Drug Discovery / AI-driven biology
Deliverable
production ML models
Required skills
In vitro pharmacology strategy, biophysical assay design (SPR, GCI, nanoDSF, MST), novel modality expertise (TPD, molecular glues, peptides), CRO study management, team leadership, LLM agentic workflows, in silico hypothesis testing
Preferred skills
Experience with induced proximity, quantitative assay development (HiBiT, NanoBRET, TR-FRET), medicinal chemistry collaboration
Technologies
SPR, GCI, nanoDSF, Spectral Shift, MST, HiBiT, NanoBRET, TR-FRET, LLM agentic workflows
Responsibilities
Set in vitro pharmacology vision and go/no-go criteria for exploratory programmes; design biochemical and biophysical screening cascades; lead a team of research investigators; manage CRO and academic studies; champion LLM agentic workflows for experimental design; collaborate with ML teams on platform builds
Seniority
Senior, hands-on IC with team leadership
