Senior Research Investigator (Biologics Computational Science), London
Core
Design novel large molecule therapeutics and develop computational methods to predict biologics properties using AI and machine learning.
Role type
Senior Research Investigator (Biologics Computational Science)
Builds
Novel protein-based therapeutics and predictive models for biologics discovery
Domain
Biotechnology / Drug Discovery / Computational Biology
Deliverable
production ML models
Required skills
Python programming, computational modeling for biologics, sequence-based property prediction (affinity, developability, immunogenicity), data analysis, model benchmarking, active learning strategies
Preferred skills
Structural modeling of biologics, generative design methods, experience with ADCs or multispecifics, pharma/biotech industry experience
Technologies
Python, generative AI, machine learning frameworks, 3D protein structure tools
Responsibilities
Identify opportunities for computational modeling in biologics discovery, develop methods to predict biologics properties from sequence, apply computational methods to discover novel therapeutics, analyze lab experiment data, determine data generation strategies for model improvement, develop methods for predicting functional properties based on biophysical constraints
Seniority
Senior, hands-on IC
