Research Leader (Toxicology), London
Core
Own safety assessment strategy for drug discovery projects from inception to regulatory submission, optimizing assets with an AI-first approach and guiding the development of AI predictive toxicology models.
Role type
Senior IC project toxicologist (drug discovery)
Builds
Safety assessment packages, regulatory documents, and AI-driven toxicology models for small molecules and biologics
Domain
Biotechnology / Pharmaceutical drug discovery / AI in toxicology
Deliverable
production ML models
Required skills
Non-clinical safety strategy design, IND package filing, SAR understanding of toxicology liabilities, regulatory guideline expertise, CRO management, cross-functional collaboration
Preferred skills
Board certification, experience with peptides and new modalities, AI/ML application in drug discovery
Technologies
AI/ML platforms for toxicology prediction
Responsibilities
Design screening cascades and mechanistic experiments to mitigate safety risks; Define regulatory safety assessment packages; Author and defend toxicology sections of regulatory documents; Oversee data generation campaigns with CROs to support AI model development; Empower team members and foster a culture of continuous learning
