Scientist II, LNP, Process Development & Manufacturing
Core
Design and execute LNP formulation studies, execute LNP production, and support process characterization, technology transfer, and manufacturing readiness for LNP-based drug products.
Role type
Senior IC process development scientist (LNP manufacturing)
Builds
LNP-based therapeutics for external clients
Domain
Biopharmaceuticals / Lipid Nanoparticle manufacturing
Required skills
LNP formulation & optimization, tLNP engineering via bioconjugation, GMP process development, scale-up to GMP manufacturing, LNP purification, analytical characterization (DLS, zeta potential, encapsulation efficiency, lipid quantification), automated manufacturing systems operation (PNI/Cytiva, Knauer, TFF), data analysis for delivery performance
Preferred skills
Targeted LNP ligand conjugation strategies, analytical method development (UPLC/HPLC-CAD), mRNA process unit operations (IVT, chromatography), Design of Experiments (DoE), statistical analysis software (JMP)
