Scientist, Delivery Screening Technology, Horns Lab
Core
Lead development of pooled screening technology to measure and engineer biological nanoparticles for delivering molecular cargo into cells.
Role type
Senior IC scientist (synthetic biology & drug delivery)
Builds
Quantitative molecular readouts, pooled libraries of engineered delivery vehicles, and scalable screening platforms
Domain
Synthetic biology, cell biology, drug delivery, nanomedicine
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Pooled screening design & execution, NGS data analysis, mammalian cell culture & engineering, flow cytometry, Python/R programming, quantitative experimental design, troubleshooting
Preferred skills
Mammalian synthetic biology, protein engineering, directed evolution, cell biology (endocytosis, receptor trafficking), virology, animal handling, drug delivery/nanomedicine experience
Technologies
NGS, flow cytometry, Python, R, mammalian cell culture systems
Responsibilities
Design and validate molecular reporters for cargo delivery efficiency; construct pooled libraries and execute sequencing-based screens; scale platforms from proof-of-concept to large multiplexed screens; analyze sequencing data and develop analysis pipelines; mentor Research Associates; present research findings at conferences
Seniority
Senior, hands-on IC
