Scientist, Neurodegeneration
Core
Lead scientific research to discover and validate therapeutic targets for reversing brain aging and treating neurodegenerative diseases using rodent models and human tissue analysis.
Role type
Senior IC neurodegeneration scientist
Builds
Preclinical research programs and therapeutic target validation for CNS diseases
Domain
Biotech / Neurodegeneration / CNS therapeutics
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
neurodegeneration disease biology, rodent model design and execution, brain tissue processing and histology, quantitative pathology readouts, in vivo surgical and behavioral techniques, therapeutic modality fluency (AAV, ASOs, small molecules), statistical study design, scientific rigor and reproducibility
Preferred skills
omics data analysis (transcriptomics, proteomics), bioinformatics programming (Python/R), spatial biology, high-content quantitative histology
Responsibilities
Design and execute in vivo studies using rodent models of neurodegeneration; Process and analyze rodent and human brain tissue (dissection, sectioning, characterization); Develop quantitative readouts for pathology markers (protein aggregation, neuroinflammation, cell loss); Collaborate with pharmacology, histology, and computational teams; Establish technical standards for experimental rigor and data integrity; Contribute to program strategy and go/no-go decisions
Seniority
Senior, hands-on IC