Senior Scientist, LNP, Process Development & Manufacturing
Core
Lead LNP formulation studies, process characterization, and technology transfer to support the manufacturing of LNP-based therapeutics.
Role type
Senior Scientist, LNP Process Development & Manufacturing
Builds
LNP-based drug products for external clients and partners
Domain
Biopharmaceuticals / Lipid Nanoparticle (LNP) manufacturing
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
LNP formulation & optimization, tLNP engineering via bioconjugation, GMP process development, scale-up, analytical characterization (DLS, zeta potential, encapsulation efficiency, lipid quantification), automated manufacturing systems operation (PNI/Cytiva, Knauer, TFF), data analysis & troubleshooting
Preferred skills
targeted LNP development, ligand conjugation strategies, analytical method development (UPLC/HPLC-CAD), mRNA process unit operations (IVT, chromatography), Design of Experiments (DoE), JMP statistical software
Responsibilities
Lead execution of LNP formulation studies for process characterization and manufacturing readiness; characterize LNP/tLNP formulations using analytical techniques; analyze experimental data to identify process improvements; support commercial team with work package evaluations; collaborate with cross-functional teams and external clients on scale-up and tech transfer
Seniority
Senior, hands-on IC