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Scientist I, QC Analytical

The Hearth - Columbus, OH💼 Full-time🗓 2026-08-04 → 2026-09-26

Core

Execute analytical testing, method validation, and troubleshooting for gene therapy products (AAV vectors, plasmids, cell banks) in a cGMP environment.

Role type

Scientist I, QC Analytical (Subject Matter Expert)

Builds

In-process, release, and stability testing data for gene therapy products

Domain

Biotechnology / Gene Therapy / Quality Control

Deliverable

production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work

Required skills

cGMP compliance, analytical method execution, troubleshooting, data interpretation, root cause analysis, regulatory documentation, mentoring junior staff, EQMS/LIMS proficiency

Preferred skills

Advanced degree (Master's/PhD), SME in nucleic acid/protein/cell-based assays, experience with ddPCR/qPCR/CE/AUC/TCID50

Technologies

ddPCR, qPCR, CE, AUC, TCID50, ELISA, LIMS, EQMS

Responsibilities

Perform in-process, release, and stability testing for viral vector/gene therapy products; Function as SME for nucleic acid, protein, or cell-based assays; Support troubleshooting of processes/assays; Conduct OOS investigations and implement CAPAs; Author and review QC documentation (SOPs, protocols); Provide technical guidance and mentorship to junior team members; Manage tracking and trending of testing data.

Seniority

Individual Contributor, entry-to-mid level with SME expectations

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