Ingénieur d'études en expérimentation in vivo et biologie cellulaire F/H
Core
Develop in vivo and in vitro models of acute myeloid leukemia (AML) in immunodeficient mice and primary cell cultures to study chemotherapy resistance and identify new therapeutic strategies.
Role type
Research laboratory biologist (in vivo/in vitro)
Builds
Mouse xenograft and syngeneic leukemia models, primary cell cultures
Domain
Oncology / Hematology / Preclinical research
Deliverable
physical/clinical work
Required skills
In vivo animal experimentation, Primary cell culture, Flow cytometry, Western blot, Immunofluorescence, Molecular biology (cloning/transfection), Data analysis
Preferred skills
Prior experience in in vivo experimentation
Technologies
NSG mice, B6 mice, Confocal microscopy
Responsibilities
Inject cells intravenously and monitor grafts in murine models, Perform in vitro functional studies on patient-derived cells, Treat and validate experimental data, Train internal staff on biological techniques, Maintain laboratory hygiene and safety rules
Seniority
Junior to Mid-level, hands-on IC