Preclinical Programme Leader, Cardiovascular & Metabolic Diseases
Core
Lead discovery and preclinical development programs for novel therapeutics targeting chronic and complex diseases, driving from target validation through candidate selection.
Role type
Senior Preclinical Program Leader (Drug Discovery)
Builds
Novel therapeutic candidates for chronic and complex diseases
Domain
Biopharmaceuticals / Cardiovascular & Metabolic Diseases
Required skills
Program leadership, in vitro/in vivo research strategy, pharmacology interpretation, assay development, disease biology expertise, external partner management, SOP establishment, team mentoring
Preferred skills
Hands-on laboratory expertise, IND-enabling development experience, systems-level disease understanding
Technologies
Cell-based screening platforms, mechanistic biology assays, in vivo pharmacology, pharmacokinetics, pharmacodynamics, biomarker development
Responsibilities
Own scientific and operational strategy for discovery-stage programs, design and execute screening cascades, interpret pharmacology and efficacy datasets, manage external research partners, build and mentor scientific teams
Seniority
Senior, hands-on IC with program management