Principal Biologist
Core
Lead biological support for early-stage drug discovery projects, identifying and validating targets to advance novel small molecule candidates into the pipeline.
Role type
Principal Biologist (Early Drug Discovery)
Builds
Novel therapeutic candidates (small molecules) for oncology and immuno-oncology
Domain
Biopharmaceuticals / Drug Discovery / Oncology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Target identification and validation, Hit-to-lead transition, In vitro assay design, In vivo model selection, CRO management, Oncology/Immuno-oncology expertise, Molecular biology, Pharmacology, Project management in multidisciplinary teams
Preferred skills
Industrial research experience, Risk identification in projects, Strategic alignment with business goals
Technologies
CRO platforms, In vivo assay systems, In vitro screening cascades
Responsibilities
Drive new drug discovery project ideas by identifying and validating targets with clear unmet needs; Support early innovation activities with molecular insights; Integrate successful projects into the research pipeline; Design and maintain screening cascades; Interact with external CROs to identify appropriate models for high-quality datasets.
Seniority
Senior, hands-on IC