Director, Genomics & ctDNA Bioinformatics
Core
Lead bioinformatics strategy and hands-on analysis for genomic and ctDNA biomarker studies across discovery, translational research, and clinical development to support oncology drug development.
Role type
Director, Genomics & ctDNA Bioinformatics
Builds
Reproducible workflows for sequencing quality control, variant detection, copy-number analysis, ctDNA quantification, and predictive/molecular response models.
Domain
Oncology, Genomics, ctDNA, Bioinformatics
Deliverable
production ML models
Required skills
Next-generation sequencing data analysis, Bioinformatics workflow development, Statistical modeling, Data integration, Benchmarking study design, Python/R proficiency, Scientific leadership
Preferred skills
Liquid biopsy and ctDNA analysis, Somatic variant calling, Machine learning/AI application, Oncology biomarker development, Multimodal data modeling
Technologies
Python, R, Next-generation sequencing platforms
Responsibilities
Lead bioinformatics strategy and analysis for genomic and ctDNA studies; Develop and evaluate reproducible workflows for genomic analyses and ctDNA quantification; Design rigorous benchmarking studies for assays and pipelines; Build statistical and predictive models integrating genomic and clinical data; Define analysis plans and validation criteria; Communicate analytical findings to multidisciplinary teams.
Seniority
Director, strategic leadership with hands-on technical execution