Project Toxicologist, Director – Oncology Targeted Delivery (OTD) Safety Science, Clinical Pharmacology and Safety Sciences (Cambridge, MA or Gaithersburg, MD)
Core
Lead toxicology strategies for novel targeted oncology therapies (radioconjugates, ADCs, small molecules) to predict, assess, and mitigate safety risks from discovery to regulatory submission.
Role type
Director, Project Toxicologist (Oncology R&D)
Builds
Investigative toxicology programs and regulatory submissions for oncology drug candidates
Domain
Oncology drug discovery and development (pharmaceutical/biotech)
Required skills
regulatory toxicology, investigative toxicology, oncology drug discovery, IND filing support, in vitro/in silico/in vivo safety assessment, cross-functional project leadership, scientific communication
Preferred skills
radioconjugates expertise, antibody–drug conjugates (ADCs) expertise, small-molecule oncology therapeutics knowledge
Technologies
organ-on-chip, imaging, omics
Responsibilities
Design and oversee regulatory and investigative toxicology programs; Apply toxicology expertise to anticipate clinical safety risks; Integrate emerging technologies to address complex safety questions; Present scientific conclusions to governance bodies; Maintain expertise in regulatory standards and preclinical safety; Provide strategic toxicology input for in-licensing and due diligence
Seniority
Director, strategic leadership & mentorship