Scientist, GPCR Biology - San Diego, CA
Core
Design, build, and run cell-based GPCR assays to discover and characterize modulators of taste and oral sensation receptors.
Role type
Scientist, GPCR Biology (PhD level)
Builds
Cell-based assays for agonists/antagonists/modulators discovery
Domain
Food science / GPCR pharmacology / Sensory biology
Required skills
GPCR biology, pharmacology, assay development, molecular biology, mammalian cell culture, taste receptor expertise, data analysis (R/Python)
Preferred skills
Sweet/bitter taste receptor structure/function, in silico drug discovery (docking/AI), receptor binding assays
Technologies
Ca²⁺ flux, cAMP, IP-One/IP3, β-arrestin, reporter gene, BRET/FRET, SPRM, molecular docking, structure-based modeling, R, Python
Responsibilities
Design and optimize cell-based GPCR assays; drive pharmacology and structure–function investigations; collaborate with Data Science teams on in silico approaches; document and communicate results.
Seniority
Senior, hands-on IC