Research Scientist, Life Sciences (Large Molecules, Process Development)
Core
Research scientist leading antibody process development and manufacturing to validate AI-designed protein sequences and enable IND-enabling studies.
Role type
Senior IC research scientist (biologics process development)
Builds
End-to-end expression and purification workflows for antibodies and recombinant proteins, scaling from plate-based to gram quantities
Domain
Life Sciences / Biologics Manufacturing / Antibody Development
Deliverable
physical/clinical work
Required skills
Antibody process development, mammalian cell expression (HEK293, CHO), affinity capture chromatography, analytical characterization (SEC, LC-MS, SPR), formulation development, CMC planning, technology transfer
Preferred skills
Upstream/downstream development, laboratory automation, GMP manufacturing, statistics/coding for data analysis, AI/ML tools in life sciences
Technologies
Protein A, IMAC, HEK293, CHO, SEC, CE-SDS, icIEF, LC-MS, DLS, SPR, BLI
Responsibilities
Develop and run expression/purification processes end-to-end; characterize products using analytical panels; build and scale laboratory workflows; evaluate AI-designed antibodies for manufacturability; plan CMC path to IND; coordinate technology transfer with external manufacturers
Seniority
Senior, hands-on IC