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Principal Software Architect

US🌐 Remote💼 Full-time💰 $168,000–$168,000🗓 2026-08-31 → 2026-09-26

Core

Lead the design and evolution of AI-enabled software platforms, translating business needs into scalable, secure, and responsible technical solutions for clinical data cloud products.

Role type

Principal Software Architect (AI & Cloud)

Builds

Enterprise-grade AI-enabled software platforms, AI-assisted workflows, and intelligent automation features for life sciences organizations.

Domain

Life Sciences / Healthcare / Cloud / AI

Deliverable

production ML models | product features | infrastructure

Required skills

Software architecture and design, Microsoft .NET, relational and non-relational database design, cloud-native platforms, AI system design patterns, SaaS deployment patterns, responsible AI practices, data governance, observability, MLOps.

Preferred skills

Evaluating new AI technologies, full-stack enterprise application development, leading software engineering teams, mentoring architects and engineers, prompt engineering, retrieval-augmented generation, agentic AI patterns.

Technologies

.NET, Python, AWS, Azure, LLMs, agentic AI frameworks, MLOps tools.

Responsibilities

Research and evaluate emerging AI, machine learning, and cloud technologies; analyze existing features and system designs for scalability and AI-readiness; document architectural patterns including AI integration and model lifecycle; define reference architectures for AI capabilities; promote responsible AI practices and compliance; guide teams in using AI-assisted engineering tools.

Seniority

Principal, strategy & mentorship

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