Senior Scientist, Downstream Process Development R&D
Core
Design and execute small-scale downstream process development studies for recovery and purification of recombinant proteins expressed in mammalian cell culture.
Role type
Senior Scientist, Downstream Process Development R&D
Builds
Robust, efficient, and scalable downstream strategies for early- and late-phase clinical programs
Domain
Biopharmaceuticals / Bioprocess Engineering
Required skills
recombinant protein downstream process development, protein chemistry, protein analytics, technology transfer, bioprocess manufacturing, experimental design, data interpretation, technical documentation, AI tool usage
Preferred skills
mammalian and microbial/yeast expression systems, pilot-scale manufacturing transfer, process validation, statistical experimental design, biologics drug development lifecycle
Technologies
ChatGPT, Microsoft Copilot, data acquisition systems, process control systems
Responsibilities
Design and execute small-scale downstream process development studies; Analyze experimental data to refine hypotheses for recovery and purification; Contribute to process characterization, validation strategies, and regulatory filings; Author technical reports and present results to cross-functional teams; Identify opportunities for operational efficiency; Support change initiatives for business infrastructure and technologies
Seniority
Senior, hands-on IC