Scientist II
Core
Develop and execute immunogenicity, PK/PD, and biomarker assays for preclinical and clinical use; perform molecular biology, ligand binding, cell culture, and histology workflows to support gene therapy and bioanalytics programs.
Role type
Senior IC scientist (bioanalytical methods & biomarkers)
Builds
Bioanalytical datasets and assay deliverables for preclinical and clinical studies
Domain
Biotechnology / Gene therapy / Bioanalytics
Required skills
AAV vector experience, PCR/qPCR/ddPCR, RNA-seq, cell culture, ligand binding assays, molecular cloning, bioanalytical assay development, clinical pharmacology concepts, histology/IHC/ISH
Preferred skills
LC-MS familiarity, experience with large sample sets
Technologies
ddPCR, RNA-seq, MSD, ELISA, LC-MS
Responsibilities
Develop and execute immunogenicity, PK/PD, and biomarker assays; perform molecular biology and nucleic acid manipulations; conduct ligand binding and cell-based assays; execute cell culture and sample preparation; prepare histology samples and perform IHC/ISH; review and interpret bioanalytical datasets; summarize findings for study teams.
Seniority
Senior, hands-on IC