CareerPlan

Senior Scientist I, Computational Protein Design

Somerville, MAFull-time2026-10-21 → 2026-11-11
Hybrid

Core

Develop computational technologies and lead applied platform research to expand protein therapeutics by creating reusable methods, scoring tools, and agentic systems for protein design and optimization.

Role type

Senior IC computational protein design scientist (platform research)

Builds

Reusable computational methods, scoring/benchmarking tools, agentic systems, and validated molecular capabilities for therapeutic development

Domain

Biotechnology / Computational Protein Design / Generative Biology

Deliverable

production ML models

Required skills

Python, PyTorch, JAX, protein structure modeling, sequence-structure-function relationships, biophysics, generative design, benchmarking, hypothesis formulation, experimental design

Preferred skills

LLM-enabled agents, multi-agent systems, scientific copilots, tool use, planning, evaluation loops

Technologies

Python, PyTorch, JAX

Responsibilities

Lead technology development and applied platform research; Build and evaluate reusable protein engineering capabilities; Engineer and validate new molecular capabilities; Scale scientific capabilities with ML and engineering teams; Build agentic systems for therapeutic protein design; Enable new therapeutic applications; Transfer and disseminate successful approaches

Seniority

Senior, hands-on IC with independent leadership