CareerPlan

Scientist I, Computational Protein Design

Somerville, MAFull-time$140k–$196k2026-10-21 → 2026-11-11
Hybrid

Core

Drive therapeutic protein design strategy by combining computational expertise with biochemical understanding to translate hypotheses into end-to-end design campaigns and integrate AI-designed proteins with experimental data.

Role type

Scientist I, Computational Protein Design (hands-on IC)

Builds

End-to-end protein design campaigns, reusable design capabilities, and agent-enabled computational workflows for therapeutic programs

Domain

Generative biology / Therapeutic protein design / Machine learning

Deliverable

production ML models

Required skills

Protein engineering, de novo protein design, protein optimization, antibody engineering, Python, experimental design, structural biology, statistical modeling

Preferred skills

Machine learning, AI-agent workflows, workflow orchestration, programmatic interfaces

Responsibilities

Translate therapeutic hypotheses into design and data-generation plans; execute protein design campaigns and interpret results; identify capability gaps to improve methods and workflows; serve as interface between computational models and experimental validation; develop agent-enabled computational workflows; communicate data-driven design recommendations to cross-functional teams

Seniority

Individual Contributor (IC), Scientist I