CareerPlan

Senior Scientist I, Protein Analytics & Biophysics

Somerville, MAFull-time$125k–$165k2026-10-19 → 2026-10-22

Core

Lead and execute hands-on analytical and biophysical workflows to assess protein quality, stability, developability, and molecular interactions for discovery programs and an AI-powered drug design platform.

Role type

Senior Scientist I, Protein Analytics & Biophysics

Builds

Analytical characterization, separation science, and biophysical workflows for protein-based medicines

Domain

Biopharmaceuticals / Protein Science / Analytical Chemistry

Deliverable

production ML models

Required skills

Biophysical characterization (stability, aggregation, self-association), Protein separation science (chromatography), SPR and binding technologies, Mass spectrometry and proteomics, Experimental design and troubleshooting, Method development

Preferred skills

Molecular barcoding, Machine-learning-enabled data integration, Mentoring and technical leadership

Technologies

SEC, IEX, HIC, capillary electrophoresis, SPR, BLI, Mass Spectrometry, Molecular barcoding

Responsibilities

Lead and execute hands-on analytical and biophysical workflows; Develop, optimize, and troubleshoot separation workflows; Perform binding analyses with emphasis on SPR; Contribute to mass spectrometry workflows; Design experiments and interpret data; Represent the function on cross-functional project teams; Operate and maintain laboratory instrumentation

Seniority

Senior, hands-on IC