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Senior ML Scientist, Biological Systems

San Francisco, CA💼 Full-time💰 $268,000–$268,000🗓 2026-09-15 → 2026-09-26

Core

Build domain models for perturbation, genetic, and multimodal experimental data to connect biological mechanisms with therapeutic opportunities, focusing on interpretable structures and uncertainty quantification.

Role type

Senior IC machine learning scientist (biological systems)

Builds

Domain models for high-dimensional biological data, experiment-selection methods, and agentic workflows for scientific decision-making

Domain

Life sciences / computational biology / AI for drug discovery

Deliverable

production ML models

Required skills

High-dimensional biological data modeling, Generalization under structured sparsity, Uncertainty quantification and calibration, Bayesian hierarchical modeling, Mechanistic and probabilistic modeling, Active learning and optimal experimental design, Model deployment in scientific workflows, Research problem formulation and execution

Preferred skills

Neural differential equations, Simulation-based inference, Lab-in-the-loop systems, Pharmacokinetic/pharmacodynamic modeling

Technologies

Bayesian inference frameworks, ODE solvers, Active learning libraries, Model serving infrastructure

Responsibilities

Translate biological questions into rigorous ML problem formulations, Partner with experimental scientists to guide data generation and model validation, Design benchmarks connecting model performance to biological consequence, Support integration of domain models into agentic workflows, Lead ambiguous research problems from formulation through execution, Communicate findings to technical and cross-functional audiences

Seniority

Senior, hands-on IC with research leadership

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