Senior Bioinformatics Scientist
Core
Develop and optimize secondary analysis algorithms and biomarkers for clinical oncology using next-generation sequencing data to support precision medicine.
Role type
Senior Bioinformatics Scientist (Clinical Oncology)
Builds
DRAGEN secondary analysis platform and oncology assays
Domain
Genomics / Clinical Oncology
Deliverable
production ML models
Required skills
Bioinformatics, Computational Biology, Statistics, NGS analysis, C++ software development, Python programming, Algorithm development
Preferred skills
Oncology domain expertise, Experience with minimal residual disease (MRD) and methylation analysis
Technologies
DRAGEN, Next-Generation Sequencing (NGS), C++, Python
Responsibilities
Assess and improve existing secondary analysis algorithms for somatic variant calling and tumor biomarker detection; Prototype and evaluate novel NGS algorithms for clinical oncology applications; Analyze sequencing data at the read level to identify opportunities for algorithmic improvements; Design, execute, and interpret experiments in partnership with R&D teams; Support the development and optimization of oncology assays through advanced bioinformatics analysis; Collaborate across multidisciplinary teams to troubleshoot challenges and implement production-ready solutions.
Seniority
Senior, hands-on IC