Bioinformatics Scientist
Core
Design, automate, and execute advanced bioinformatics analyses and reproducible pipelines to support biomarker analysis, translational research, and clinical development.
Role type
Senior IC Bioinformatics Scientist (NGS/Omics & AI)
Builds
Production-grade bioinformatics pipelines, multi-omics integration frameworks, and agentic AI workflows for drug development and clinical trials.
Domain
Biopharmaceuticals / Genomics / Multi-omics / AI
Deliverable
production ML models | production ML models
Required skills
Python, R, NGS analysis workflows, single-cell RNA-seq, spatial transcriptomics, workflow engines (Nextflow, Snakemake), containerization (Docker/Singularity), cloud/HPC environments, deep learning models, foundation models, LLMs, RAG, agentic AI workflows, statistical reasoning, data standards (FASTQ, BAM/CRAM, VCF/MAF, HDF5/AnnData/Seurat), public genomics databases (TCGA, GTEx, GEO, SRA, dbGaP, cBioPortal, ClinVar, COSMIC, gnomAD, UniProt), benchmarking and validation frameworks, unit/integration testing.
Preferred skills
C/C++, Java, GPU computing, single-cell/spatial omics experience, agentic AI workflows.
Technologies
Nextflow, Snakemake, Docker, Singularity, AWS, Git, TCGA, GTEx, GEO, SRA, dbGaP, cBioPortal, ClinVar, COSMIC, gnomAD, UniProt, Seurat, AnnData, HDF5, FASTQ, BAM, CRAM, VCF, MAF, RAG, LLMs
Responsibilities
Design, develop, validate, and maintain end-to-end bioinformatics analysis pipelines for genomics, transcriptomics, single-cell, spatial omics, proteomics, and epigenomics; Implement reproducible workflows using workflow engines and containerization ensuring provenance and CI/CD; Lead optimization of production-grade pipelines for runtime efficiency, scalability, and cost-effectiveness; Design and implement scalable multi-omics integration frameworks combining genomic, transcriptomic, proteomic, imaging, and clinical data; Develop state-of-the-art agentic workflows for QC, tool selection, execution optimization, and results interpretation; Define and execute QC, benchmarking, and validation strategies for pipelines and algorithms; Collaborate with internal labs and CROs to onboard new assays and maintain data transfer specifications; Produce technical documentation, statistical methods descriptions, and contribute to regulatory submissions and publications.
Seniority
Senior, hands-on IC
