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Principal Software Engineer, Instrument Simulations

Alewife, Cambridge, MA💼 Full-time💰 $204,000–$204,000🗓 2026-06-15 → 2026-07-31

Core

Architect and lead the development of simulation infrastructure and integration layers connecting AI-driven experimental design with physical robotic systems for closed-loop scientific discovery.

Role type

Principal Software Engineer (Instrument Simulations)

Builds

High-fidelity simulation environments, integration patterns for heterogeneous hardware, and APIs for automation infrastructure.

Domain

Laboratory automation, robotics, AI-driven scientific discovery

Deliverable

production ML models | product features | infrastructure

Required skills

C++, Python, Java, system architecture, CI/CD, hardware-software integration, team leadership, mentoring

Preferred skills

Ph.D. in CS/Engineering, laboratory automation systems experience, organizational change management, agile project delivery

Technologies

C++, Python, Java

Responsibilities

Architect simulation environments for lab instrumentation, design hardware integration patterns, develop APIs for scientist/AI interaction, establish engineering best practices, mentor engineering teams

Seniority

Principal, hands-on IC with leadership

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