Research Associate, Process Development
Core
Develop synthetic routes and process chemistry to produce milligram-to-gram quantities of active pharmaceutical ingredients (API) for oligonucleotide therapeutics.
Role type
Process development chemist (oligonucleotide synthesis)
Builds
Oligonucleotide API and process components
Domain
Pharmaceutical / Oligonucleotide synthesis
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Oligonucleotide synthesis, purification, ultrafiltration, conjugation, lyophilization, Design of Experiments (DOE), Proven Acceptable Range (PAR), scale-up, GMP compliance, technical reporting
Preferred skills
Emerging analytical methods, state-of-the-art benchmarking
Technologies
Microsoft products, Internet
Responsibilities
Execute process development experiments and DOE/PAR studies; document analyses and write technical reports for technology transfer; optimize processes and transfer to mid/kilo-scale GMP manufacturing; study project objectives and emerging trends in synthesis development.