Principal Research Scientist I, Process Chemistry
Core
Develop biocatalytic processes for the scalable synthesis of active pharmaceutical ingredients (APIs) including small molecules, peptides, and antibody-drug conjugates.
Role type
Principal Research Scientist I, Process Chemistry (Biocatalysis)
Builds
Scalable chemical manufacturing processes for API production
Domain
Pharmaceutical process chemistry / Biocatalysis
Deliverable
production ML models | product features
Required skills
Biocatalysis, Synthetic organic chemistry, Recombinant DNA techniques, Protein expression, Directed evolution, High-throughput experimentation (HTE), AI/ML for chemical synthesis, Process development
Preferred skills
Enzyme discovery, Automation technologies, Scientific leadership
Technologies
AI/ML tools, Bioinformatics platforms, HTE platforms
Responsibilities
Implement biocatalytic methods to solve complex synthetic problems; Engineer biocatalysts with improved activity/selectivity/stability; Accelerate enzyme screening and optimization using AI/ML and HTE; Lead project teams for process development; Author technical reports, patents, and scientific publications.
Seniority
Principal, hands-on IC with strategic input
