Principal Research Scientist II, Gastroenterology, Immunology Discovery Research
Core
Lead discovery research in Gastroenterology/IBD, managing a team to deliver novel therapeutics from target identification through preclinical development and first-in-human studies.
Role type
Principal Research Scientist (Strategic Leadership & Team Management)
Builds
Novel therapeutics for autoimmune diseases (IBD)
Domain
Biopharmaceuticals / Immunology / Gastroenterology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Mucosal immunology expertise, in vitro and in vivo pharmacology, humanized CIVM models, PKPD assessment, strategic research planning, team leadership, risk mitigation, cross-functional collaboration
Preferred skills
Experience with organoid-based models, publication authoring, mentoring diverse teams
Technologies
Humanized CIVMs, organoid-based models, PKPD tools
Responsibilities
Lead and develop a high-performing research team; oversee planning and execution of in vitro and in vivo pharmacology studies; direct drug discovery programs from conception to clinical candidate selection; devise and implement research strategies addressing critical scientific objectives; collaborate with multidisciplinary teams and external partners; develop risk mitigation strategies; promote knowledge sharing through publications and presentations; mentor and train direct reports.
Seniority
Principal, strategic leadership & mentorship