Principal Research Scientist I
Core
Design and execute safety assessment strategies for discovery-stage programs using in silico, in vitro, and in vivo tools to support pipeline advancement in preclinical safety.
Role type
Principal Research Scientist I (Toxicologist)
Builds
Safety assessment strategies and data integration for therapeutic area programs
Domain
Pharmaceutical preclinical safety / Toxicology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
in vitro safety study design and interpretation, in silico tool utilization, in vivo study execution, experimental design for decision-making, scientific literature review, cross-functional collaboration, team mentorship and supervision, original research strategy generation
Preferred skills
People leadership and management experience, DABT board certification, cross-functional project team experience in pharmaceutical development
Technologies
in silico tools, in vitro models, NAMs (New Approach Methodologies), imaging, toxicogenomics
Responsibilities
Design and execute safety strategies leveraging internal/external resources and models; Develop and deploy in vitro tools and utilize appropriate endpoints; Identify and resolve key project hurdles; Communicate across cross-functional teams and leadership; Incorporate new scientific information into safety strategies; Pursue exploration and experiments for data-driven decision-making; Mentor and supervise team members; Collaborate to identify areas of scientific advancement
Seniority
Principal, hands-on IC with mentorship responsibilities
