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Director, Computational HitGen / LeadGen Team Lead

North Chicago, IL, us💼 Full-time🗓 2026-08-06 → 2026-09-26

Core

Lead the computational HitGen/LeadGen team to develop AI-native drug discovery methods for predicting binding affinities, pharmacological properties, and sampling chemical spaces for AbbVie's small molecule portfolio.

Role type

Director, Computational Drug Discovery (HGLG Team Lead)

Builds

Computational tools and workflows for hit/lead generation and property prediction

Domain

Pharmaceutical R&D / AI-native drug discovery / Small molecule chemistry

Deliverable

production ML models | product features

Required skills

Strategic thought leadership, team leadership and mentorship, cross-functional collaboration, modern computational drug design, scientific publication, benchmarking experiments, workflow development

Preferred skills

Established external footprint and network, experience with diverse drug discovery campaigns

Technologies

AI-native drug discovery tools, binding affinity prediction, pharmacological property prediction, chemical space sampling

Responsibilities

Lead development of cutting-edge methods for binding affinity and property prediction; Guide team in benchmarking model performance; Provide strategic advice to senior management; Author scientific publications and present at conferences; Establish processes for selecting computational approaches

Seniority

Director, global team leadership

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