Scientist, Antibody Developability
Core
Build and validate an automated, high-throughput antibody developability assessment panel (thermostability, aggregation, solubility, etc.) to separate binders from manufacturable therapeutics and connect experimental data to in-silico predictions.
Role type
Senior Scientist, Antibody Developability
Builds
A productized, automated developability assessment service for antibody campaigns
Domain
Biotechnology / Antibody Discovery / Protein Engineering (via careerplan.io/jobs/206ef8b0-0a46-4a55-8aa9-ed495c165d53-scientist-antibody-developability-at-adaptyv)
Deliverable
production ML models
Required skills
Antibody developability assays, Thermostability (DSF/nanoDSF), Aggregation/Self-association (SEC, HIC, DLS), Solubility assessment, Chemical liability assessment, Lab automation, In-silico prediction integration, Data structuring
Preferred skills
Data scripting, Structured dataset analysis
Responsibilities
Build and validate developability assessment panel hands-on, Turn panel into a productized high-throughput service, Partner with lab automation to scale assays, Work with software/ML teams to structure data, Interpret results and advise customers on liabilities, Set scientific standards for developability data
Seniority
Senior, hands-on IC