CareerPlan

Principal Scientist and Group Leader, Antibody Engineering

South San Francisco, USFull-time$142k2026-10-02 → 2026-11-11
On-site · United States

Core

Lead a bench-focused laboratory team to pioneer breakthrough protein technologies and translate exploratory antibody science into transformational medicines for patients.

Role type

Principal Scientist and Group Leader (Antibody Engineering)

Builds

Next-generation clinical candidates and novel biotherapeutic platforms

Domain

Biopharmaceuticals / Antibody Engineering

Required skills

protein engineering, protein stability characterization, protein-protein interaction analysis, molecular format development, cross-functional collaboration, scientific publication record, patent generation

Preferred skills

experience with induced proximity, receptor agonism, targeted therapeutics, antibody-drug conjugates (ADCs), structural biology

Technologies

None explicitly listed

Responsibilities

Direct and manage a bench-focused laboratory team, develop novel methods and predictive assays to de-risk therapeutic formats, define molecular requirements for projects, drive platform innovation across emerging mechanisms, cultivate a high-performing lab culture, collaborate with multidisciplinary research partners

Seniority

Principal, hands-on IC with team leadership