Scientist 3, Immunology and Ophthalmology, Sudharsan Lab
Core
Design and execute research strategies using advanced retinal cellular systems to validate targets, elucidate disease mechanisms, and advance novel therapies for retinal diseases, specifically Age-Related Macular Degeneration (AMD).
Role type
Senior IC stem cell biologist (retinal models)
Builds
Human iPSC-derived retinal models (RPE, photoreceptors) and cell-based assays
Domain
Biopharma / Ophthalmology / Stem Cell Biology
Required skills
Human iPSC culture and differentiation, cell culture-based assay development, experimental design, data reproducibility, peer-reviewed publication record
Preferred skills
Retinal cell biology, gene editing, omics technologies (single-cell RNA-seq, spatial transcriptomics), 3D retinal organoids, target engagement assays
Technologies
iPSC workflows, single-cell RNA-seq, spatial transcriptomics, proteomics, 3D organoid platforms
Responsibilities
Develop human iPSC-derived retinal models and design cell-based assays to validate targets and study AMD pathogenesis; Implement new experimental workflows and analytical tools as priorities evolve; Maintain rigorous experimental design and electronic lab records; Collaborate with interdisciplinary teams; Communicate research findings at internal forums and external conferences
Seniority
Senior, hands-on IC