Scientist 3, Biochemical and Cellular Pharmacology
Core
Design and execute sophisticated biochemical and cell-based assays to evaluate drug candidates in cardiovascular, renal, and metabolic areas, supporting lead finding through optimization.
Role type
Senior IC biochemical and cellular pharmacology scientist
Builds
Innovative drug candidates for cardio-metabolic therapeutics
Domain
Pharma / Cardio-metabolic disease
Required skills
mammalian and primary cell culture, stable cell line generation, gene-editing (CRISPR), GPCR signaling pathways, ligand-receptor binding kinetics, microplate-format biochemical and cellular assays (HTRF, AlphaScreen, luminescence), laboratory robotics (Bravo, Tecan, Echo), data analysis (GraphPad Prism, Genedata, Excel, Python, R)
Preferred skills
cardiovascular/renal/metabolic disease expertise, flow cytometry, ELISA, high-content image analysis, high-throughput screening
Responsibilities
Design and execute rigorous experiments independently, troubleshoot issues, analyze complex data, document results, drive screening efforts across multiple projects, pioneer novel assay platforms, drive automation and efficiency using laboratory robotics, collaborate across multidisciplinary teams
Seniority
Senior, hands-on IC
