Scientist 3, Biochemical and Cellular Pharmacology
Core
Design and execute sophisticated biochemical and cell-based assays to evaluate drug candidates in cardiovascular, renal, and metabolic areas, supporting lead finding through optimization.
Role type
Senior IC biochemical and cellular pharmacology scientist
Builds
Innovative drug candidates for cardio-metabolic therapeutics
Domain
Pharma/Biotech, Cardio-metabolic disease, Receptor pharmacology
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
mammalian and primary cell culture, stable cell line generation, gene-editing (CRISPR), GPCR signaling pathway analysis, ligand-receptor binding kinetics, microplate biochemical/cellular assays (HTRF, AlphaScreen, luminescence), experimental design, data analysis with computational tools, laboratory robotics operation
Preferred skills
cardiovascular/renal/metabolic disease expertise, flow cytometry, ELISA, high-content image analysis, lab automation, high-throughput screening, data visualization (GraphPad Prism, Genedata, Python, R)
Responsibilities
Design and execute rigorous experiments independently, troubleshoot issues, analyze complex data, document results, drive screening efforts across multiple projects, pioneer novel assay platforms, drive automation and efficiency using laboratory robotics
Seniority
Senior, hands-on IC