Sr. Scientist - Translational PBPK Modeling
Core
Lead translational PBPK modeling and simulations to support small molecule drug discovery and development, optimizing leads and supporting clinical candidate selection.
Role type
Senior Scientist (Translational PBPK Modeling)
Builds
PBPK models and simulations for small molecule drug candidates
Domain
Pharmaceutical R&D / Pharmacokinetics
Deliverable
production ML models | product features
Required skills
PBPK modeling, quantitative pharmacology, Simcyp, GastroPlus, PK-Sim, drug metabolism, pharmacokinetics
Preferred skills
Phoenix, R, NONMEM, SimBiology, Python, DMPK project leadership, multi-modality drug development
Technologies
Simcyp, GastroPlus, PK-Sim, Phoenix, R, NONMEM, SimBiology, Python
Responsibilities
Strategize, plan, execute, and report PBPK modeling and simulations independently; present work to cross-functional teams and regulatory bodies; represent DMPK in multi-functional project teams; lead DMPK strategy and design non-clinical studies
Seniority
Senior, hands-on IC
