Principal Scientist, Medical Physicist
Core
Lead translational dosimetry analysis and radiopharmaceutical dose modelling for the research and development of new oncology drugs and therapies.
Role type
Principal Scientist, Medical Physicist (Radiopharmaceuticals)
Builds
Radiopharmaceutical imaging and therapeutic agents
Domain
Oncology / Nuclear Medicine / Radiopharmaceuticals
Deliverable
production ML models
Required skills
Mathematical pharmacokinetic modeling, Radiopharmaceutical biodistribution and kinetics, Dosimetry calculations, PET/SPECT data analysis, Physiologically based pharmacokinetics (PBPK), Compartmentalization modelling, Alpha-emitter expertise, Python, Matlab, R, 3D-RD-S, MIM, MIRDcalc, OLINDA, GATE, SIMIND
Preferred skills
Novel radioisotope development, Global dosimetry guidelines, AI application for team execution
Technologies
3D-RD-S, MIM, MIRDcalc, OLINDA, Torch, GATE, SIMIND, SAAM II, SimBiology, Python, Matlab, R, SPSS, ITK-snap, 3D slicer, Elastix
Responsibilities
Design experiments and perform dosimetric data analysis from imaging modalities like PET and SPECT, Analyze preclinical and clinical imaging data to advance animal-to-human dose projection, Identify and advise best practices for image data quality control in preclinical research, Explore new technologies and modelling approaches to improve radiopharmaceutical development, Provide technical support, training and problem-solving solutions to cross-functional teams, Apply AI to improve team execution and decision-making
Seniority
Principal, hands-on IC with strategic leadership