Principal Scientist, Portfolio & gRED Interface-Biologics, AI for Drug Discovery (AIDD)
Core
Leading the application of machine learning models to active large molecule (antibody) drug discovery projects at Genentech, serving as a technical advisor to leadership, and building a team of computational scientists.
Role type
Principal Scientist, Portfolio & gRED Interface (AI for Drug Discovery)
Builds
Production ML models for developability, functional modeling, and design optimization applied to active gRED antibody projects.
Domain
Biopharma / AI for Drug Discovery (AIDD) / Large Molecule (Antibody) Engineering
Deliverable
production ML models
Required skills
Machine learning for biologics, antibody engineering, biophysical modeling, portfolio science, team leadership, strategic planning, stakeholder management, scientific communication
Preferred skills
Experience translating research to portfolio impact, navigating organizational complexity, mentoring junior scientists
Technologies
Machine learning frameworks, computational biology tools, large molecule design platforms
Responsibilities
Drive portfolio impact by applying ML models to active gRED projects; Interface with gRED leadership as a trusted technical advisor; Lead the Large Molecule portfolio modeling team and set research direction; Develop and execute a technical strategy for ML in antibody discovery; Navigate complex stakeholder landscapes to align priorities; Identify and own high-impact research initiatives.
Seniority
Principal, hands-on IC with leadership responsibilities
