Scientist 2, Neuroscience Discovery & iPSC Assay Development
Core
Generate CNS cell models from human iPSCs, execute functional assays, and support disease-relevant phenotyping for neuroscience discovery and drug development.
Role type
Scientist 2, Neuroscience Discovery & iPSC Assay Development
Builds
CNS cell lineages (neurons, glia) and functional assay platforms for neuroscience pipeline programs
Domain
Neuroscience / Cell Biology / Drug Discovery
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
human iPSC maintenance and banking, directed differentiation into CNS cell types, molecular biology, advanced optical imaging, biochemistry, plate-based or high-content imaging assays, independent experimental design, data documentation
Preferred skills
CRISPR/Cas9 gene editing in iPSCs, arrayed/pooled CRISPR screens, single-cell RNA sequencing (scRNA-seq) workflows, data analysis with R or Python
Technologies
Electronic Lab Notebook (ELN), NGS, R, Python
Responsibilities
Culture, bank, and QC human iPSCs; differentiate iPSCs into CNS cell lineages; manage primary neuronal cultures; design and execute cell-based assays; support genetic and pharmacological proof-of-concept studies; generate and analyze experimental data; present findings to multidisciplinary teams; oversee iPSC lab operations
Seniority
Mid-Senior, hands-on IC