PhD Candidate in Functional Genomics and Pancreatic Cancer Research; part time 65% (m/w/d)
Core
Investigate therapeutically relevant genetic dependencies and drug combinations in pancreatic ductal adenocarcinoma using high-throughput Cas13d-based genetic interaction screens and molecular/cell biological validation.
Role type
PhD Candidate in Functional Genomics and Cancer Research
Builds
Preclinical models and data for rational combination therapies in pancreatic cancer
Domain
Oncology / Functional Genomics / Molecular Biology
Deliverable
research
Required skills
Cell culture, transfection, RNA and protein analysis, immunoblotting, microscopy, quantitative data analysis, scientific writing
Preferred skills
CRISPR-based technologies, genetic screens, proteomics, next-generation sequencing, bioinformatic data analysis
Technologies
Cas13d, CRISPR, NGS, proteomics platforms
Responsibilities
Perform and analyze high-throughput genetic interaction screens; Plan and conduct molecular and cell biological experiments to validate targets; Investigate rational combination therapies with RAS/KRAS inhibitors; Present research findings at conferences and contribute to publications
Seniority
PhD Candidate, research-focused