Biochemist (m/w/d)
Core
Design, expression, purification, characterization, and modification of antibodies and recombinant proteins to support therapeutic development.
Role type
Senior IC biochemist (antibody and protein)
Builds
Therapeutic antibody programs advancing toward first-in-human studies
Domain
Biopharmaceuticals / Antibody-drug conjugates / Protein biochemistry
Required skills
antibody and protein biochemistry, molecular cloning, protein expression, chromatography, analytical characterization, construct design, protein modification
Preferred skills
postdoctoral or industry experience, HPLC method development, SPR-based binding kinetics, antibody humanization, carbohydrate biology
Technologies
ÄKTA chromatography, SPR, ELISA, Western blotting, thermal shift assays
Responsibilities
Design protein and antibody constructs, perform chemical/enzymatic modification of antibodies, characterize antibody affinity and stability, develop protein purification workflows, coordinate external research projects, document results and evaluate scientific literature
Seniority
Senior, hands-on IC