Senior Principal Scientist, Molecular Assays & Genomics Team Lead (Cell Therapy Translational Research)
Core
Lead the Molecular Assays & Genomics team to develop and implement molecular biomarker assays supporting translational research, clinical development, and patient-safety assessments for cell and gene therapy programs.
Role type
Senior Principal Scientist, Team Lead (Molecular Assays & Genomics)
Builds
Fit-for-purpose molecular and genomic assays for cell and gene therapy programs
Domain
Biotechnology / Cell Therapy / Genomics
Required skills
Molecular biology, Genomics, Assay development and validation, qPCR/ddPCR, Next-generation sequencing, Team leadership, Scientific strategy, Laboratory oversight, Data quality management, Cross-functional collaboration
Preferred skills
PhD in molecular biology/genetics, Clinical assay implementation experience, Cell and gene therapy expertise, Genomic applications (WGS, TCR sequencing), GCLP/GLP laboratory experience
Technologies
ddPCR, Next-generation sequencing, RT-qPCR, Whole-genome sequencing, TCR sequencing
Responsibilities
Lead team direction, mentoring, and talent development; Own assay strategy and scientific standards; Translate research questions into assay approaches; Lead assay development, qualification, and clinical implementation; Provide technical leadership across molecular platforms; Partner with program leads on safety and development objectives; Oversee data quality and technical interpretation; Evaluate and select laboratory capabilities; Assess new molecular technologies; Communicate scientific recommendations to stakeholders.
Seniority
Senior Principal, Hands-on IC with People Leadership