Sr Associate Scientist, Neuroscience, Exploratory Biology
Core
Characterize disease-relevant biology using primary and iPSC-derived neuronal and glial systems to support target validation and mechanism-of-action studies for early-stage neuroscience programs.
Role type
Senior Associate Scientist (Exploratory Biology, Neuroscience)
Builds
Early-stage neuroscience programs
Domain
Biopharmaceuticals / Neuroscience
Required skills
Primary neuronal culture, iPSC-derived neuron/glia culture, genome editing, genetic perturbation, immunofluorescence, microscopy, high-content imaging, qPCR, JESS, ELISA, MEA, experimental design, data analysis
Preferred skills
Assay development, mammalian cell culture, data visualization, strong foundational neuroscience knowledge
Technologies
qPCR, JESS, ELISA, MEA, microscopy, high-content imaging platforms
Responsibilities
Design, execute, and troubleshoot experiments to explore neurobiological mechanisms; Culture and maintain primary neuronal cultures, iPSC-derived neurons and glia; Perform target validation studies including genome editing and genetic perturbation; Conduct mechanism-of-action studies to characterize compound or genetic effects; Apply immunofluorescence, microscopy, and high-content imaging/analysis to assess cellular phenotypes; Analyze, document, and present data with rigor and reproducibility
Seniority
Senior Associate (4+ years experience with Bachelor's or 2+ years with Master's)