Senior Associate Scientist, Neuroscience, In Vitro Pharmacology
Core
Develop and execute scalable in vitro assays for high-throughput screening to identify novel therapeutic targets and modulators in neuroscience drug discovery.
Role type
Senior Associate Scientist, In Vitro Pharmacology
Builds
Scalable screening pipelines for compound/oligo campaigns
Domain
Neuroscience drug discovery / In vitro pharmacology
Required skills
Mammalian cell culture, Assay development, High-content imaging, Genetic perturbation screens (siRNA/ASO/CRISPR), Data analysis, Troubleshooting
Preferred skills
Primary neuronal or iPSC-derived cultures, Automation/robotics platforms, Large dataset handling
Responsibilities
Develop, optimize, and validate assays for high-throughput and high-content screening applications; Execute compound screening campaigns, including cell viability and reporter-based assays; Design and implement genetic perturbation screens; Perform high-content imaging and automated image analysis; Maintain and scale mammalian cell culture systems; Troubleshoot assay performance issues; Analyze large screening datasets; Document protocols and results; Partner cross-functionally with automation, informatics, and target validation teams.
Seniority
Mid-Senior level (4+ years exp with Bachelor's or 2+ years with Master's)