Scientist, Non-Viral Delivery Process Sciences
Core
Design and execute hypothesis-driven studies to develop robust, scalable manufacturing strategies for complex non-viral delivery systems (LNPs) and translate targeted LNP science into scalable process technologies.
Role type
Scientist, Non-Viral Delivery Process Sciences
Builds
Scalable manufacturing approaches for targeted LNP platforms
Domain
Biopharmaceutical manufacturing / Process Development
Required skills
mechanistic process science, LNP formulation, bioconjugation, scale-down modeling, design of experiments (DoE), statistical analysis, analytical characterization, cross-functional collaboration
Preferred skills
Chemical Engineering or Bioengineering background, hands-on experience with rapid mixing (microfluidic/impingement jet), tangential flow filtration (TFF), purification, physicochemical/biophysical characterization, data-driven process development
Technologies
microfluidic mixing, impingement jet mixing, TFF, UF/DF, DLS, zeta potential, HPLC, LC/MS, SDS-PAGE
Responsibilities
Design and execute hypothesis-driven studies to deepen mechanistic process understanding; Develop and optimize end-to-end targeted LNP processes spanning formulation, bioconjugation, purification, and downstream processing; Establish mechanistic process understanding of targeting moiety conjugation; Develop and apply fit-for-purpose scale-down models; Apply design of experiments and statistical analysis to establish process–attribute–performance relationships; Partner with Analytical Development to implement process analytical technologies; Identify and implement emerging process technologies; Collaborate cross-functionally to translate early process understanding into scalable manufacturing approaches
Seniority
Mid-Senior level Scientist