PhD Student (m/f/d) 13914 / Brückeninstitut für Experimentelle Tumorforschung (BIT)
Core
Conduct high-level interdisciplinary research on the earliest mechanisms of therapy resistance in melanoma, specifically investigating fibroblast heterogeneity and tumor–immune interactions in the context of immune checkpoint inhibitor response.
Role type
PhD Student (Research Associate)
Builds
Experimental data and scientific insights on melanoma therapy resistance and immune modulation.
Domain
Oncology / Cancer Immunology / Molecular Biology
Deliverable
research
Required skills
Molecular and cellular biology techniques, Cell culture, Flow cytometry, Microscopy, Gene expression analysis (qPCR), Cytokine/chemokine profiling, Data analysis and interpretation, English (fluent)
Preferred skills
Multiplex/spatial imaging experience, Bioinformatics or biostatistics experience, Experience with immune-oncology functional assays
Technologies
Phenocycler, Spatial transcriptomics, Confocal microscopy, AI-supported data integration
Responsibilities
Decipher fibroblast heterogeneity implications for immune checkpoint inhibitor response, Investigate fibroblast, melanoma, and T cell interactions, Perform multiplex imaging and spatial characterization of tumor–immune interactions, Execute in vitro and ex vivo functional assays, Analyze and integrate experimental results with computational partners, Present scientific results at meetings and conferences