Wissenschaftliche*r Mitarbeiterin*s (m-w-d)
Core
Leading the clinical-translational work package of the O3PeT consortium to identify biomarkers and personalized combination therapies for ovarian cancer using organoid models, multi-omics data, and AI-driven analysis.
Role type
Senior Research Scientist (Clinical-Translational Oncology)
Builds
Personalized combination therapies and biomarker identification for ovarian cancer
Domain
Oncology / Precision Medicine / Bioinformatics
Deliverable
production ML models
Required skills
Next-Generation Sequencing, Confocal Fluorescence Microscopy, Tumor and RNA Biology, Cell Biology (Flow Cytometry, FACS, Live-cell imaging), Drug testing in 2D/3D/Organoid models, Statistical analysis, Grant writing
Preferred skills
Single-Cell RNA Sequencing, Spatial Transcriptomics, CRISPR-based methods, Animal experiments (with FILASA-B certification), Multiplex Immunohistochemistry
Technologies
Leica SP8X, STELLARIS, RNA-seq, Spatial transcriptomics
Responsibilities
Coordinate clinical-translational work packages, Develop clinical research strategy integrating clinical/histopathological data with organoid results, Plan and execute NGS and multiplex immunohistochemistry projects, Analyze drug combination tests in organoid models, Publish scientific papers and secure third-party funding