Senior Associate Scientist - Analytical Development
Core
Develop and validate analytical methods for proteins, nucleic acids, and lipids to support cell line, upstream, and downstream development, and transfer methods to QC for validation.
Role type
Senior Associate Scientist - Analytical Development
Builds
Robust analytical assays and methods for mRNA proteins/mAbs
Domain
Biopharmaceuticals / Analytical Chemistry
Deliverable
production ML models | product features | dashboards & analysis | research | client delivery | infrastructure | physical/clinical work
Required skills
Biochemical/biophysical and immunological concepts, SDS-PAGE/Agarose Gel analysis, ELISA, Western Blot, HPLC, Capillary Electrophoresis (CE), cIEF, product binding/activity assays, qPCR, Sanger Sequencing, LCMS peptide mapping, intact mass analysis, released N-glycan analysis, experimental design (DoE), Analytical Quality by Design (AQbD), GMP documentation, Good Documentation Practices (GDP)
Preferred skills
None stated
Technologies
LCMS, HPLC, CE, cIEF, qPCR, Sanger Sequencing
Responsibilities
Execute analysis of proteins and biological macromolecules from mammalian cell culture, develop robust assays using DoE and AQbD, record and verify experimental data, support sample shipments to clients, maintain project timelines, perform lab housekeeping and sterilization, write procedural SOPs, mentor or train others
Seniority
Senior, hands-on IC
